Is compound interest hindered by separation into two accounts?

I have my company matched monthly contribution going into my 401k of about 300$ a month and 200$ a month going into a broad index fund in an individual trader account. Would I be better off just upping my employment contributions? I did like having more liquidity so eventually I can save up and buy some real estate. Any flaws in my set up? I’m trying to take a little income and a side hustle, and create some financial safety.