BTSV Prediction: Flipping the Ghostflower dynamic
In ATSV, we saw Miles trying to make the moves on Gwen, who turned down his advances due to her fear of the canon coming true.
In BTSV, I think we will see that dynamic flipped. After seeing that canon events are NOT set in stone, Gwen will be more hopeful and try to pursue Miles. Miles, however, due to his distrust of Gwen and the discovery of the canon events, will try to push her away. He'll feel jaded and unworthy after seeing the horrible state of Earth-42 that he feels responsible for. He'll also become afraid of getting Gwen killed if she falls for him, but she will prove otherwise and give him back the confidence to defy his own canon event.
This will eventually end with them getting together.