The Antichrist

Damien Thorn (The Omen) is one of the most popular depictions of the Antichrist in pop culture.

Adrian Woodhouse (Rosemary's Baby) is the other most famous depiction of the Antichrist.

Johan Liebert (Monster) may or may not literally be the Antichrist, but he is still explicitly compared to the Beast. The catalyst of the plot, when Tenma saved him from the bullet in his head is likely a reference to Revelation 13:3: "And I saw one of his heads as it were wounded to death; and his deadly wound was healed: and all the world wondered after the beast."