Penicillin only thing that has helped . Why ?

Through this whole 3.5 year journey penicillin is the only thing that has helped me.

I am taking oral penicillin I started on Monday and it has been the only thing to help me at all . All the other antibiotics I even took in high doses with no reaction.

Does penicillin hit Lyme and infections or is it possible I had something else that gave me encephalitis type systems ?

I know penicillin hits Syphilis and gonnorrhea.