Can Blast Rate vary significantly?
Hi everyone! Need guidance/hope or any wisdom. 33F, AMH-0.47, AFC-8. No MFI
My husband and I only tried two months before I decided to go into a fertility doc just to get a green light and came out with a DOR dx. We want two children ideally so RE recommended IVF to proactively freeze some embryo’s. Just had my first retrieval last week and I had 4 mature eggs retrieved and 2 fertilized and they kept progressing but none made it to blast by day 7 (stopped at cleavage though none arrested. That cycle was estrogen patch prime and antagonist. 300 gonal/ 225 menopur/ganrelix.
We are going to switch to a mini stim protocol with clomid and menopur this next cycle (ganrelix also). The Process has been so difficult as I feel every turn I get bad news (have one blocked tube which I didn’t know about, and first cycle was cancelled because 1 dominant follicle).
Question for others as now I feel like my egg quality is awful— but I keep reminding myself of the stats and numbers, though it’s hard.
Have others had cycles with no blasts and then had success with making blasts in the next cycle? And them being euploid? I’m not ready to give up yet and I keep reminding myself that DOR doesn’t mean you can’t conceive naturally. But also feeling like what if the fact that I can’t make any blasts this round means that my egg quality is too far gone, and we are scrapping at the bottom of the barrel already.
Sincerely Appreciate any info or personal experience - hopeful or not.
(Also this last round we did conventional IVF versus ICSI per rec from RE because no MFI but perhaps we should do ICSI next round?)